

NOT ONLY DIABETES AND OBESITY! The Potential Cancer-Preventive Effects Expected from GLP-1 Receptor Agonists
Masahiro Kami, M.D., Ph.D. President, Medical Governance Research Institute, Tokyo, Japan Table of Contents Lowering Blood Glucose and Reducing Body Weight GLP-1 Drugs Suppress Chronic Inflammation and Reduce Cancer Risk Obesity-Related Cancer Risk Reduced by 40% Through Factors Beyond Weight Loss Diet and Exercise Therapy Are Important, But… I would like to write once again about GLP-1 receptor agonists—the drugs that have been in the spotlight as so-called “weight-loss dr
2 days ago


Hidden Dehydration: Are You Losing Focus in the Heat? By the Time You Feel Thirsty, Dehydration May Already Be Underway
Kana Yamamoto, M.D., Ph.D Physician, Medical Governance Research Institute In her regular column “A Little Medical Notebook,” where she discusses everyday topics and news from a medical and health perspective, Dr. Kana Yamamoto, an internist at Navitas Clinic and the Medical Governance Research Institute, examines the issue of “hidden dehydration.” When people hear the word “dehydration,” many think of older adults or infants. However, active, healthy young people who are c
6 days ago


Sharp-Minded Even in Their 80s: What Is a “SuperAger,” the Kind of Person Everyone Aspires to Be?
Mutsuko Ohnishi, MD, Internal medicine physician in Boston, USA Contents 1. What Is a SuperAger? 2. What Happens in the Brain? 3. Can New Neurons Be Generated in the Adult Brain? 4. What Did the Researchers Investigate? 5. New Neurons Can Develop Even in the Adult Brain 6. What Happens in the Brain of a Person with Alzheimer’s Disease? 7. Four Habits Shared by SuperAgers8. It Is Never Too Late to Improve Your Lifestyle “It seems I’ve become so forgetful lately. I guess it
Aug 27


Living with Panic Attacks: A Physician’s Personal Reflection
Kana Yamamoto, M.D., Ph.D Physician, Medical Governance Research Institute The “Imitecho (Medical Examination Notebook)” column features reflections by a physician on health and everyday life. In this installment, Dr. Kana Yamamoto, a physician at Navitas Clinic and the Medical Governance Research Institute, reflects on panic attacks from both a professional and personal perspective. Shortly after I moved to the United States, I was constantly confused by small, everyday sit
Aug 15


Tsubokura-sensei’s Radiation Classroom #559:Driving Change by Incorporating Women’s Voices
Masaharu Tsubokura, M.D., Ph.D. Chief Professor, Department of Radiation Health Management, School of Medicine, Fukushima Medical University Following the Great East Japan Earthquake and the accident at the Fukushima Daiichi Nuclear Power Plant operated by Tokyo Electric Power Company, the way evacuation shelters are organized has undergone significant review. During this process, many accounts of the inconveniences and anxieties experienced by women were recorded, serving a
Aug 9


An American doctor spent time in a small isolation room in Prague
Hisanori Murasawa, 5th-year Student, General Medicine, First Faculty of Medicine, Charles University On May 21, I was going daily between the university's affiliated hospital for surgical rotations. After lectures and practical exercises held during the day, I had studied with classmates to prepare for the last final exam of the year. Amidst all this, there was a moment when everyone's hands paused. This is because news broke that an American doctor suspected of being infecte
Jul 24


Reflections on Home-Based End-of-Life Care in an Aging Society
OneVoice OneAction Across the nation, young physicians are bringing a new energy to the field. What sparks their resolve, and where is their journey leading them? Here, we pause to capture the heart and soul behind their mission. Makoto Kosaka, M.D., Physician, Orange Home Care Clinic; currently Director, Kokoiruyo Clinic (“I’m Here With You” Clinic) Feeling the Pulse of Our Aging Society in Home Care I am currently in my fourth year as a physician, working at the Orange
Jul 19


Observing "Home Medical Treatment Innovations" that are rooted in the local community
Akihiko Ozaki, M.D., Ph.D. Physician at the Medical Governance Research Institute Visit to the Higashi Osaka Clinic On September 6th, I visited Okamoto Internal Medicine Clinic in Higashiosaka City. The clinic's director, Dr. Masayuki Okamoto, graduated from Nada High School and went on to Kyoto Prefectural University of Medicine. After working at his alma mater, he opened a clinic in his hometown of Higashi-Osaka. Dr. Okamoto was a senior at high school of Dr. Masahiro Kam
Jul 11


Why was a post-disaster reconstruction tax successfully introduced in Japan, a country known for strong resistance to taxation, following the Great East Japan Earthquake?
Takashi Miyaji, internal medicine Clinical Education and Training Center, Akita University Hospital 【Key points 】 •Key concepts emphasized by the Reconstruction Design Council included “solidarity” and the “responsibility of the working generation.” •Income tax, which allows for contributions based on individuals’ ability to pay, served as the main source of funding. •Policies should be aligned with public values and provide a clear direction for society as a whole. While tax
Jun 21


Article on the Experience of Evacuating Dialysis Patients
Akihiko Ozaki, M.D., Ph.D. Physician at the Medical Governance Research Institute This year, we mark another 3.11. A full 14 years have passed since the 2011 Great East Japan Earthquake and the subsequent nuclear power plant accident. Since 2012, I have spent the majority of my time in Fukushima. Thanks to various connections, I have been fortunate enough to continuously be involved in both clinical practice and research to convey the health impacts and lessons learned from t
Jun 13


THE 20TH SYMPOSIUM OF THE FIELD-DRIVEN HEALTHCARE REFORM PROMOTION COUNCILCutting-Edge Clinical Research and DevelopmentIslet Transplantation for the Radical Cure of Diabetes
Shinichi Matsumoto Visiting Professor, Department of Surgery Graduate School of Medicine, Kobe University At the 20th Symposium of the Field-Driven Healthcare Reform Promotion Council, I was given the opportunity to deliver a lecture for the first time in quite some time. I spoke about islet transplantation, a curative treatment for diabetes. I would like to share the content of that lecture through MRIC. THE ROAD TO TRANSPLANTATION RESEARCH When I was in the second yea
Apr 10


A Discussion on Drug CostsThe Trump Administration’s Efforts to Lower Drug Prices140th
Tetsuya Tanimoto, MD. Chairman of Accessible Railway Medical Services Tetsuikai Medical Corporation. Director of Navitas Clinic Kawasaki In May, the drug-pricing policy announced by the Trump administration went beyond a simple reduction in U.S. drug prices and took on the nature of a global political and economic strategy. Its impact is expected to ripple across the entire global pharmaceutical system. Behind the policy, which aims to align U.S. drug prices with those of cou
Mar 13


Some people might think, "The 'Chokubi' problem? Why now?"
Akihiko Ozaki, M.D., Ph.D. Physician at the Medical Governance Research Institute To explain it again, "Chokubi" is a term for doctors who go "straight" or “direct” (choku) into aesthetic medicine (bi) immediately after finishing their initial clinical residency, without first passing through a university medical department or a general hospital. Reports last year indicated that several hundred doctors annually are choosing this path. I (the author) have been interested in th
Mar 1


The U.S.-based doping-approved competition “Enhanced Games” is nothing more than a human experiment that leads athletes to destruction — the fear as told by an Olympic silver medalist and a physician
Masahiro Kami, M.D., Ph.D. President, Medical Governance Research Institute, Tokyo, Japan Recently, it was announced that the “Enhanced Games” will be held in Las Vegas, USA, in May 2026. Participants may take part as subjects in clinical trials. Events such as sprinting, swimming, and weightlifting will be held, but what is particularly noteworthy is that athletes can choose from three options: 1. participating naturally without using any drugs, 2. participating unde
Feb 15


Let's discuss the cost of medicine. Are Japan's top-selling drugs really worth it?No. 139
Akihiko Ozaki, M.D., Ph.D. Physician at the Medical Governance Research Institute In recent years, the breast cancer field, which the author is responsible for, has seen a continuous succession of new drug developments. In 2024, capivasertib ("Truqap") for hormone receptor-positive breast cancer with specific gene mutations (PIK3CA, AKT1, PTEN) was approved in March, sacituzumab govitecan ("Trodelvy") for triple-negative breast cancer in November, and datopotamab deruxtecan (
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