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A “bottom up” treatment for Ebola that could have been used in West Africa

Author: David S.Fedson, MD (dfedson@wanadoo.fr) Affiliation: Former Professor of Medicine, University of Virginia School of Medicine Editor: Motoi Miura, Tetsuya Tanimoto More than 11,000 people died as a result of the Ebola outbreak in West Africa. Aside from conventional supportive care, no specific treatment was available. In most treatment units, more than 50% of the patients died. We now know that many of them could have survived. Patients who die of Ebola have elevated plasma levels of pro-inflammatory cytokines. The same thing is seen in patients with sepsis, and in sepsis patients these findings are associated with endothelial dysfunction and the loss of endothelial barrier integrity

Social studies of science conflicts: dealing with scientific fraud in Japan

Author: Pablo Ariel Pellegrini (ppellegrini@unq.edu.ar) Affiliation: CONICET, Universidad Nacional de Quilmes, Instituto de Estudios sobre la Ciencia y la Tecnología, Buenos Aires, Argentina​ Editor: Miura Motoi, Akihiko Ozaki There are many cases of research misconduct, including scientific fraud, in the biomedical sciences. But there are also fraud cases in physics, mathematics, informatics, engineering and social sciences. It doesn’t seem to be a problem of a specific kind of science; all disciplines have registered fraud cases. It is a generalized issue, and an issue that is not so much spoken about. Is a subject that usually turns awkward. The reason is that in any social sphere, impost

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